The film is supposedly based on Dicillo's experiences making his first feature, Johnny Suede, which starred a very young and very difficult Brad Pitt (Oblivion's obnoxious lead Chad Palomino (James Legros) gives us a good hint of what that must have been like.)
See that look of shock and disbelief on Buscemi's face in the top link around 1:02, the one that gradually fades into a grimace of despair by 1:20? That look, I think, encapsulates Dicillo's reaction to feature-length filmmaking.
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